7WV5

ectoTLR3-poly(I:C)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Toll-like receptor 3	polymer	689	78423.4	2	UniProt (O15455) Pfam (PF13855) Pfam (PF13516) Pfam (PF00560)	Homo sapiens (human)
2	C (E)	RNA (46-MER)	polymer	46	13993.4	1		synthetic construct
3	D (F)	RNA (46-MER)	polymer	46	15143.8	1		synthetic construct
4	E, F, G, I, J... (C, D, G, I, J...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	8	In PDB GlyTouCan (G42666HT)
5	H, M (H, M)	beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	2	In PDB GlyTouCan (G40894EI)
6	O, P, Q, R, S... (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)

Sequence modifications

A, B: 27 - 697 (UniProt: O15455)

PDB	External Database	Details
Ala 24	-	expression tag
Asp 25	-	expression tag
Pro 26	-	expression tag
Ser 698	-	expression tag
Gly 699	-	expression tag
Arg 700	-	expression tag
Leu 701	-	expression tag
Val 702	-	expression tag
Pro 703	-	expression tag
Arg 704	-	expression tag
Gly 705	-	expression tag
Ser 706	-	expression tag
His 707	-	expression tag
His 708	-	expression tag
His 709	-	expression tag
His 710	-	expression tag
His 711	-	expression tag
His 712	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	185984.0
Branched	Number of molecules	10
	Total formula weight	4892.6
Non-Polymers*	Number of molecules	10
	Total formula weight	2212.1
All*	Total formula weight	193088.6

*Water molecules are not included.