7WU7

Prefoldin-tubulin-TRiC complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	1	Prefoldin subunit 1	polymer	122	14234.5	1	UniProt (O60925) Pfam (PF01920) In PDB	Homo sapiens (human)
2	2	Prefoldin subunit 2	polymer	154	16672.8	1	UniProt (Q9UHV9) Pfam (PF01920) In PDB	Homo sapiens (human)
3	3	Prefoldin subunit 3	polymer	197	22658.9	1	UniProt (P61758) Pfam (PF02996) In PDB	Homo sapiens (human)	HIBBJ46,von Hippel-Lindau-binding protein 1,VBP-1,VHL-binding protein 1
4	4	Prefoldin subunit 4	polymer	140	16160.1	1	UniProt (Q9NQP4) Pfam (PF01920) In PDB	Homo sapiens (human)	Protein C-1
5	5	Prefoldin subunit 5	polymer	140	16051.6	1	UniProt (Q99471) Pfam (PF02996) In PDB	Homo sapiens (human)	Myc modulator 1,c-Myc-binding protein Mm-1
6	6	Prefoldin subunit 6	polymer	129	14603.6	1	UniProt (O15212) Pfam (PF01920) In PDB	Homo sapiens (human)	Protein Ke2
7	A, I	T-complex protein 1 subunit alpha	polymer	556	60418.5	2	UniProt (P17987) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-alpha,CCT-alpha
8	B, J	T-complex protein 1 subunit beta	polymer	535	57567.1	2	UniProt (P78371) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-beta,CCT-beta
9	C, K	T-complex protein 1 subunit gamma	polymer	545	60613.9	2	UniProt (P49368) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-gamma,CCT-gamma,hTRiC5
10	D, L	T-complex protein 1 subunit delta	polymer	539	57996.1	2	UniProt (P50991) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-delta,CCT-delta,Stimulator of TAR RNA-binding
11	E, M	T-complex protein 1 subunit epsilon	polymer	541	59750.0	2	UniProt (P48643) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-epsilon,CCT-epsilon
12	F, N	T-complex protein 1 subunit zeta	polymer	531	58166.2	2	UniProt (P40227) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-zeta,Acute morphine dependence-related protein 2,CCT-zeta-1,HTR3,Tcp20
13	G, O	T-complex protein 1 subunit eta	polymer	543	59443.5	2	UniProt (Q99832) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-eta,CCT-eta,HIV-1 Nef-interacting protein
14	H, P	T-complex protein 1 subunit theta	polymer	547	59576.3	2	UniProt (P50990) Pfam (PF00118) In PDB	Homo sapiens (human)	TCP-1-theta,CCT-theta,Chaperonin containing T-complex polypeptide 1 subunit 8,Renal carcinoma antigen NY-REN-15
15	F, H, N, P	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	4	Chemie (ADP)

Sequence modifications

4: 1 - 134 (UniProt: Q9NQP4)

PDB	External Database	Details
His 135	-	expression tag
His 136	-	expression tag
His 137	-	expression tag
His 138	-	expression tag
His 139	-	expression tag
His 140	-	expression tag

F, N: 1 - 531 (UniProt: P40227)

PDB	External Database	Details
Phe 528	Ser 528	conflict

Contents of the asymmetric unit

Polymers	Number of chains	22
	Total formula weight	1047444.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1708.8
All*	Total formula weight	1049153.6

*Water molecules are not included.