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Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1218S rRNApolymer1873604117.81Homo sapiens
2R40S ribosomal protein S17polymer13515578.21UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS17
3b40S ribosomal protein S27polymer849480.21UniProt (P42677)
Pfam (PF01667)
In PDB		Homo sapiens (human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
4B40S ribosomal protein S3apolymer26430002.11UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
5c40S ribosomal protein S28polymer697855.11UniProt (P62857)
Pfam (PF01200)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS28
6E40S ribosomal protein S4, X isoformpolymer26329654.91UniProt (P62701)
Pfam (PF16121)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
In PDB		Homo sapiens (human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
7e40S ribosomal protein S30polymer596668.91UniProt (P62861)
Pfam (PF04758)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS30
8F40S ribosomal protein S5polymer20422913.51UniProt (P46782)
Pfam (PF00177)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS7
9H40S ribosomal protein S7polymer19422168.91UniProt (P62081)
Pfam (PF01251)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS7
10G40S ribosomal protein S6polymer24928751.91UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
11Z40S ribosomal protein S25polymer12513776.21UniProt (P62851)
Pfam (PF03297)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS25
12Y40S ribosomal protein S24polymer13315463.31UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS24
13xRNA-binding protein PNO1polymer25227970.41UniProt (Q9NRX1)
Pfam (PF22891)
In PDB		Homo sapiens (human)Partner of NOB1
14X40S ribosomal protein S23polymer14315844.71UniProt (P62266)
Pfam (PF00164)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS12
15wBystinpolymer43749673.31UniProt (Q13895)
Pfam (PF05291)
In PDB		Homo sapiens (human)
16W40S ribosomal protein S15apolymer13014865.61UniProt (P62244)
Pfam (PF00410)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS8
17uPre-rRNA-processing protein TSR1 homologpolymer80491951.21UniProt (Q2NL82)
Pfam (PF22298)
Pfam (PF08142)
Pfam (PF04950)
In PDB		Homo sapiens (human)
18T40S ribosomal protein S19polymer14516091.61UniProt (P39019)
Pfam (PF01090)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS19
19S40S ribosomal protein S18polymer15217759.81UniProt (P62269)
Pfam (PF00416)
In PDB		Homo sapiens (human)Ke-3,Ke3,Small ribosomal subunit protein uS13
20Q40S ribosomal protein S16polymer14616477.41UniProt (P62249)
Pfam (PF00380)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS9
21P40S ribosomal protein S15polymer14517076.21UniProt (P62841)
Pfam (PF00203)
In PDB		Homo sapiens (human)RIG protein,Small ribosomal subunit protein uS19
22O40S ribosomal protein S14polymer15116302.81UniProt (P62263)
Pfam (PF00411)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS11
23N40S ribosomal protein S13polymer15117259.41UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS15
24L40S ribosomal protein S11polymer15818468.81UniProt (P62280)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS17
25J40S ribosomal protein S9polymer19422641.61UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS4
26I40S ribosomal protein S8polymer20824263.41UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS8
27rMultifunctional methyltransferase subunit TRM112-like proteinpolymer12514215.41UniProt (Q9UI30)
Pfam (PF03966)
In PDB		Homo sapiens (human)
28qProbable 18S rRNA (guanine-N(7))-methyltransferasepolymer28131925.41UniProt (O43709)
Pfam (PF08241)
Pfam (PF12589)
In PDB		Homo sapiens (human)Bud site selection protein 23 homolog,Metastasis-related methyltransferase 1,Williams-Beuren syndrome chromosomal region 22 protein,rRNA methyltransferase and ribosome maturation factor
29KRRP12-like proteinpolymer1297143916.51UniProt (Q5JTH9)
Pfam (PF08161)
In PDB		Homo sapiens (human)
30M40S ribosomal protein S12polymer13214539.01UniProt (P25398)
Pfam (PF01248)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS12
31fUbiquitin-40S ribosomal protein S27apolymer15618004.01UniProt (P62979)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Homo sapiens (human)Ubiquitin carboxyl extension protein 80
32zRibosome biogenesis protein SLX9 homologpolymer23025503.31UniProt (Q9NSI2)
Pfam (PF15341)
In PDB		Homo sapiens (human)
33A40S ribosomal protein SApolymer29532883.91UniProt (P08865)
Pfam (PF00318)
Pfam (PF16122)
In PDB		Homo sapiens (human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
34C40S ribosomal protein S2polymer29331376.51UniProt (P15880)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Homo sapiens (human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
35V40S ribosomal protein S21polymer839124.41UniProt (P63220)
Pfam (PF01249)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS21
362ZINC IONnon-polymer65.41Chemie (ZN)
37qS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains35
Total formula weight1494565.2
Non-Polymers*Number of molecules2
Total formula weight449.8
All*Total formula weight1495015.1
*Water molecules are not included.

222036

PDB entries from 2024-07-03

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