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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7WTU

Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (without CK1)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1218S rRNApolymer1873604117.81Homo sapiens
2R40S ribosomal protein S17polymer13515578.21UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS17
3b40S ribosomal protein S27polymer849480.21UniProt (P42677)
Pfam (PF01667)
In PDB		Homo sapiens (human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
4B40S ribosomal protein S3apolymer26430002.11UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
5c40S ribosomal protein S28polymer697855.11UniProt (P62857)
Pfam (PF01200)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS28
6E40S ribosomal protein S4, X isoformpolymer26329654.91UniProt (P62701)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
In PDB		Homo sapiens (human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
7e40S ribosomal protein S30polymer596668.91UniProt (P62861)
Pfam (PF04758)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS30
8F40S ribosomal protein S5polymer20422913.51UniProt (P46782)
Pfam (PF00177)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS7
9H40S ribosomal protein S7polymer19422168.91UniProt (P62081)
Pfam (PF01251)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS7
10G40S ribosomal protein S6polymer24928751.91UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
11Z40S ribosomal protein S25polymer12513776.21UniProt (P62851)
Pfam (PF03297)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS25
12Y40S ribosomal protein S24polymer13315463.31UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS24
13xRNA-binding protein PNO1polymer25227970.41UniProt (Q9NRX1)
Pfam (PF22891)
In PDB		Homo sapiens (human)Partner of NOB1
14X40S ribosomal protein S23polymer14315844.71UniProt (P62266)
Pfam (PF00164)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS12
15wBystinpolymer43749673.31UniProt (Q13895)
Pfam (PF05291)
In PDB		Homo sapiens (human)
16W40S ribosomal protein S15apolymer13014865.61UniProt (P62244)
Pfam (PF00410)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS8
17uPre-rRNA-processing protein TSR1 homologpolymer80491951.21UniProt (Q2NL82)
Pfam (PF22298)
Pfam (PF08142)
Pfam (PF04950)
In PDB		Homo sapiens (human)
18tProtein LTV1 homologpolymer47554935.91UniProt (Q96GA3)
Pfam (PF04180)
In PDB		Homo sapiens (human)
19T40S ribosomal protein S19polymer14516091.61UniProt (P39019)
Pfam (PF01090)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS19
20S40S ribosomal protein S18polymer15217759.81UniProt (P62269)
Pfam (PF00416)
In PDB		Homo sapiens (human)Ke-3,Ke3,Small ribosomal subunit protein uS13
21Q40S ribosomal protein S16polymer14616477.41UniProt (P62249)
Pfam (PF00380)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS9
22P40S ribosomal protein S15polymer14517076.21UniProt (P62841)
Pfam (PF00203)
In PDB		Homo sapiens (human)RIG protein,Small ribosomal subunit protein uS19
23O40S ribosomal protein S14polymer15116302.81UniProt (P62263)
Pfam (PF00411)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS11
24N40S ribosomal protein S13polymer15117259.41UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS15
25L40S ribosomal protein S11polymer15818468.81UniProt (P62280)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS17
26J40S ribosomal protein S9polymer19422641.61UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS4
27I40S ribosomal protein S8polymer20824263.41UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS8
28rMultifunctional methyltransferase subunit TRM112-like proteinpolymer12514215.41UniProt (Q9UI30)
Pfam (PF03966)
In PDB		Homo sapiens (human)
29qProbable 18S rRNA (guanine-N(7))-methyltransferasepolymer28131925.41UniProt (O43709)
Pfam (PF08241)
Pfam (PF12589)
In PDB		Homo sapiens (human)Bud site selection protein 23 homolog,Metastasis-related methyltransferase 1,Williams-Beuren syndrome chromosomal region 22 protein,rRNA methyltransferase and ribosome maturation factor
30KRRP12-like proteinpolymer1297143916.51UniProt (Q5JTH9)
Pfam (PF08161)
In PDB		Homo sapiens (human)
31M40S ribosomal protein S12polymer13214539.01UniProt (P25398)
Pfam (PF01248)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS12
32fUbiquitin-40S ribosomal protein S27apolymer15618004.01UniProt (P62979)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Homo sapiens (human)Ubiquitin carboxyl extension protein 80
33zRibosome biogenesis protein SLX9 homologpolymer23025503.31UniProt (Q9NSI2)
Pfam (PF15341)
In PDB		Homo sapiens (human)
34qS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
35fZINC IONnon-polymer65.41Chemie (ZN)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains33
Total formula weight1476116.3
Non-Polymers*Number of molecules2
Total formula weight449.8
All*Total formula weight1476566.1
*Water molecules are not included.

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PDB entries from 2024-07-31

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