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7WTC

Cryo-EM structure of human pyruvate carboxylase with acetyl-CoA in the ground state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Pyruvate carboxylase, mitochondrialpolymer1178129799.44UniProt (P11498)
Pfam (PF00289)
Pfam (PF02786)
Pfam (PF02785)
Pfam (PF00682)
Pfam (PF02436)
Pfam (PF00364)
Homo sapiens (human)Pyruvic carboxylase,PCB
2E, H, I, J
(A, B, C, D)
5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANALnon-polymer228.34Chemie (BTI)
3F, G
(A, B)
ACETYL COENZYME *Anon-polymer809.62Chemie (ACO)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight519197.4
Non-Polymers*Number of molecules6
Total formula weight2532.4
All*Total formula weight521729.8
*Water molecules are not included.

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PDB entries from 2025-07-09

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