7WT0

human glyoxalase I (with C-ter His tag) in complex with TLSC702

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Lactoylglutathione lyase	polymer	192	21874.9	2	UniProt (Q04760) Pfam (PF00903)	Homo sapiens (human)	Aldoketomutase,Glyoxalase I,Glx I,Ketone-aldehyde mutase,Methylglyoxalase,S-D-lactoylglutathione methylglyoxal lyase
2	C, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, F (A, B)	(~{E})-3-(1,3-benzothiazol-2-yl)-4-(4-methoxyphenyl)but-3-enoic acid	non-polymer		325.4	2	Chemie (5ZO)
4	G, H (A, B)	water	water		18.0	106	Chemie (HOH)

Sequence modifications

A, B: 0 - 183 (UniProt: Q04760)

PDB	External Database	Details
Leu 184	-	expression tag
Glu 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43749.7
Non-Polymers*	Number of molecules	4
	Total formula weight	781.6
All*	Total formula weight	44531.3

*Water molecules are not included.