7WSB

The ternary complex structure of FtmOx1 with a-ketoglutarate and 13-oxo-fumitremorgin B

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Verruculogen synthase	polymer	319	35841.8	6	UniProt (Q4WAW9) Pfam (PF05721)	Aspergillus fumigatus Af293	Fumitremorgin biosynthesis protein F
2	G, L, P, S, W... (A, B, C, D, E...)	COBALT (II) ION	non-polymer		58.9	6	Chemie (CO)
3	AA, H, M, Q, T... (F, A, B, C, D...)	13-Oxofumitremorgin B	non-polymer		477.6	6	Chemie (4IL)
4	BA, I, N, R, U... (F, A, B, C, D...)	2-OXOGLUTARIC ACID	non-polymer		146.1	6	Chemie (AKG)
5	J, O (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
6	K, V (A, D)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7	CA, DA, EA, FA, GA... (A, B, C, D, E...)	water	water		18.0	137	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 2 - 291 (UniProt: Q4WAW9)

PDB	External Database	Details
Met -14	-	expression tag
Gly -13	-	expression tag
Asp -12	-	expression tag
Arg -11	-	expression tag
Gly -10	-	expression tag
Pro -9	-	expression tag
Glu -8	-	expression tag
Phe -7	-	expression tag
Trp -6	-	expression tag
Ser -5	-	expression tag
His -4	-	expression tag
Pro -3	-	expression tag
Gln -2	-	expression tag
Phe -1	-	expression tag
Glu 0	-	expression tag
Lys 1	-	expression tag
Leu 292	-	expression tag
Glu 293	-	expression tag
Val 294	-	expression tag
Asp 295	-	expression tag
Leu 296	-	expression tag
Gln 297	-	expression tag
Gly 298	-	expression tag
Asp 299	-	expression tag
His 300	-	expression tag
Gly 301	-	expression tag
Leu 302	-	expression tag
Ser 303	-	expression tag
Ala 304	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	215050.9
Non-Polymers*	Number of molecules	22
	Total formula weight	4491.9
All*	Total formula weight	219542.8

*Water molecules are not included.