7WS6

Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C	Spike protein S1	polymer	218	24823.1	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
2	H	510A5 light chain	polymer	108	11680.9	1		Homo sapiens
3	I	510A5 heavy chain	polymer	125	13744.2	1		Homo sapiens

Sequence modifications

C: 319 - 536 (UniProt: P0DTC2)

PDB	External Database	Details
Asp 339	Gly 339	variant
Leu 371	Ser 371	variant
Pro 373	Ser 373	variant
Phe 375	Ser 375	variant
Asn 417	Lys 417	variant
Lys 440	Asn 440	variant
Ser 446	Gly 446	variant
Asn 477	Ser 477	variant
Lys 478	Thr 478	variant
Ala 484	Glu 484	variant
Arg 493	Gln 493	variant
Ser 496	Gly 496	variant
Arg 498	Gln 498	variant
Tyr 501	Asn 501	variant
His 505	Tyr 505	variant

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	50248.3
All*	Total formula weight	50248.3

*Water molecules are not included.