7WRT

X-ray structure ofThermus thermophilus HB8 transketorase demonstrate in complex with TPP and D-erythrose-4-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Transketolase	polymer	672	74230.7	4	UniProt (Q5SM35) Pfam (PF00456) Pfam (PF02779) Pfam (PF22613)	Thermus thermophilus HB8
2	E, I, K, O (A, B, C, D)	THIAMINE DIPHOSPHATE	non-polymer		425.3	4	Chemie (TPP)
3	F, J, L, P (A, B, C, D)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
4	G, H, M, N (A, B, C, D)	ERYTHOSE-4-PHOSPHATE	non-polymer		200.1	4	Chemie (E4P)
5	Q, R, S, T (A, B, C, D)	water	water		18.0	183	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 651 (UniProt: Q5SM35)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	296922.9
Non-Polymers*	Number of molecules	12
	Total formula weight	2661.9
All*	Total formula weight	299584.8

*Water molecules are not included.