7WQQ
Retinoic acid receptor alpha mutant - N299H
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Retinoic acid receptor alpha | polymer | 265 | 30150.8 | 1 | UniProt (P10276) Pfam (PF00104) In PDB | Homo sapiens (human) | RAR-alpha,Nuclear receptor subfamily 1 group B member 1 |
2 | C | Peptide from Nuclear receptor coactivator 1 | polymer | 13 | 1591.9 | 1 | UniProt (Q15788) In PDB | Homo sapiens | |
3 | A | 4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxidanylidene-prop-1-enyl]benzoic acid | non-polymer | 364.5 | 1 | Chemie (5Z6) | |||
4 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A: 176 - 421 (UniProt: P10276)
PDB | External Database | Details |
---|---|---|
Met 157 | - | initiating methionine |
Lys 158 | - | expression tag |
Ser 159 | - | expression tag |
Ser 160 | - | expression tag |
His 161 | - | expression tag |
His 162 | - | expression tag |
His 163 | - | expression tag |
His 164 | - | expression tag |
His 165 | - | expression tag |
His 166 | - | expression tag |
Glu 167 | - | expression tag |
Asn 168 | - | expression tag |
Leu 169 | - | expression tag |
Tyr 170 | - | expression tag |
Phe 171 | - | expression tag |
Gln 172 | - | expression tag |
Ser 173 | - | expression tag |
Asn 174 | - | expression tag |
Ala 175 | - | expression tag |
His 299 | Asn 299 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31742.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 364.5 | |
All* | Total formula weight | 32107.1 |