7WPO
Structure of NeoCOV RBD binding to Bat37 ACE2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Angiotensin-converting enzyme | polymer | 692 | 80775.1 | 1 | UniProt (A0A7J7V5I6) Pfam (PF01401) Pfam (PF16959) In PDB | Pipistrellus pipistrellus (common pipistrelle) | |
| 2 | B | Spike glycoprotein | polymer | 194 | 21842.5 | 1 | UniProt (U5NJG5) Pfam (PF09408) In PDB | Coronavirus Neoromicia/PML-PHE1/RSA/2011 | S glycoprotein,E2,Peplomer protein |
| 3 | C | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 4 | E, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | P | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 6 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
A: 21 - 712 (UniProt: A0A7J7V5I6)
B: 380 - 573 (UniProt: U5NJG5)
| PDB | External Database | Details |
|---|---|---|
| Glu 24 | Gly 24 | conflict |
| Asp 28 | Glu 28 | conflict |
| Glu 36 | Lys 36 | conflict |
| Glu 58 | Lys 58 | conflict |
| Arg 80 | Leu 80 | conflict |
| Asn 91 | Asp 91 | conflict |
| Leu 92 | Ser 92 | conflict |
| Glu 197 | Lys 197 | conflict |
| Gly 211 | Trp 211 | conflict |
| Glu 212 | Gly 212 | conflict |
| Gln 221 | His 221 | conflict |
| Glu 305 | Asp 305 | conflict |
| Tyr 321 | Arg 321 | conflict |
| Ser 322 | Asn 322 | conflict |
| Gln 325 | Pro 325 | conflict |
| Asn 330 | Lys 330 | conflict |
| Glu 353 | Lys 353 | conflict |
| Asn 432 | Leu 432 | conflict |
| Ile 436 | Lys 436 | conflict |
| Glu 536 | Gln 536 | conflict |
| Tyr 568 | Leu 568 | conflict |
| Asn 571 | Glu 571 | conflict |
| Arg 575 | Gly 575 | conflict |
| Lys 597 | Glu 597 | conflict |
| Leu 617 | Ile 617 | conflict |
| Thr 664 | Arg 664 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 431 | Ile 431 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 102617.6 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2330.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 106053.8 |
