7WP8
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C | 83H7 light chain | polymer | 104 | 11428.6 | 1 | Mus musculus | ||
2 | D | 83H7 heavy chain | polymer | 118 | 13027.5 | 1 | Mus musculus | ||
3 | E | 2B4 heavy chain | polymer | 119 | 13681.2 | 1 | Mus musculus | ||
4 | F | Spike glycoprotein | polymer | 183 | 20803.3 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
5 | G | 2B4 light chain | polymer | 113 | 12449.8 | 1 | Mus musculus | ||
6 | H | 85F7 heavy chain | polymer | 118 | 13159.6 | 1 | Mus musculus | ||
7 | L | 85F7 light chain | polymer | 106 | 11278.5 | 1 | Mus musculus | ||
8 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
9 | L | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
F: 336 - 518 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Thr 417 | Lys 417 | engineered mutation |
Arg 452 | Leu 452 | engineered mutation |
Lys 478 | Thr 478 | variant |
Lys 484 | Glu 484 | engineered mutation |
Tyr 501 | Asn 501 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 7 |
Total formula weight | 95828.6 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 221.2 | |
All* | Total formula weight | 96474.2 |