7WP8
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | 83H7 light chain | polymer | 104 | 11428.6 | 1 | Mus musculus | ||
| 2 | B (D) | 83H7 heavy chain | polymer | 118 | 13027.5 | 1 | Mus musculus | ||
| 3 | C (E) | 2B4 heavy chain | polymer | 119 | 13681.2 | 1 | Mus musculus | ||
| 4 | D (F) | Spike glycoprotein | polymer | 183 | 20803.3 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 5 | E (G) | 2B4 light chain | polymer | 113 | 12449.8 | 1 | Mus musculus | ||
| 6 | F (H) | 85F7 heavy chain | polymer | 118 | 13159.6 | 1 | Mus musculus | ||
| 7 | G (L) | 85F7 light chain | polymer | 106 | 11278.5 | 1 | Mus musculus | ||
| 8 | H (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 9 | I (L) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
F: 336 - 518 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Thr 417 | Lys 417 | engineered mutation |
| Arg 452 | Leu 452 | engineered mutation |
| Lys 478 | Thr 478 | variant |
| Lys 484 | Glu 484 | engineered mutation |
| Tyr 501 | Asn 501 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 95828.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 96474.2 |
