7WOR
The state 2 of Omicron Spike with bispecific antibody FD01
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1285 | 142506.0 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
2 | D, F (D, F) | 16L9 Fv | polymer | 247 | 25730.0 | 2 | Homo sapiens (human) | ||
3 | E (E) | GW01 Fv | polymer | 251 | 26186.5 | 1 | Homo sapiens (human) | ||
4 | AA, BA, CA, G, H... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 23 | Chemie (NAG) |
Sequence modifications
A, B, C: 1 - 1208 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Val 67 | Ala 67 | variant |
- | His 69 | deletion |
- | Val 70 | deletion |
Ile 95 | Thr 95 | variant |
Asp 145 | Gly 142 | variant |
- | Val 143 | deletion |
- | Tyr 144 | deletion |
- | Tyr 145 | deletion |
- | Asn 211 | deletion |
Ile 209 | Leu 212 | variant |
Glu 212 | - | insertion |
Pro 213 | - | insertion |
Glu 214 | - | insertion |
Asp 339 | Gly 339 | variant |
Leu 371 | Ser 371 | variant |
Pro 373 | Ser 373 | variant |
Phe 375 | Ser 375 | variant |
Asn 417 | Lys 417 | variant |
Lys 440 | Asn 440 | variant |
Ser 446 | Gly 446 | variant |
Asn 477 | Ser 477 | variant |
Lys 478 | Thr 478 | variant |
Ala 484 | Glu 484 | variant |
Arg 493 | Gln 493 | variant |
Ser 496 | Gly 496 | variant |
Arg 498 | Gln 498 | variant |
Tyr 501 | Asn 501 | variant |
His 505 | Tyr 505 | variant |
Lys 547 | Thr 547 | variant |
Gly 614 | Asp 614 | variant |
Tyr 655 | His 655 | variant |
Lys 679 | Asn 679 | variant |
His 681 | Pro 681 | variant |
Gly 682 | Arg 682 | engineered mutation |
Ser 683 | Arg 683 | engineered mutation |
Ser 685 | Arg 685 | engineered mutation |
Lys 764 | Asn 764 | variant |
Tyr 796 | Asp 796 | variant |
Pro 817 | Phe 817 | variant |
Lys 856 | Asn 856 | variant |
Pro 892 | Ala 892 | engineered mutation |
Pro 899 | Ala 899 | engineered mutation |
Pro 942 | Ala 942 | engineered mutation |
His 954 | Gln 954 | variant |
Lys 969 | Asn 969 | variant |
Phe 981 | Leu 981 | variant |
Pro 986 | Lys 986 | engineered mutation |
Pro 987 | Val 987 | engineered mutation |
Gly 1209 | - | expression tag |
Ser 1210 | - | expression tag |
Gly 1211 | - | expression tag |
Tyr 1212 | - | expression tag |
Ile 1213 | - | expression tag |
Pro 1214 | - | expression tag |
Glu 1215 | - | expression tag |
Ala 1216 | - | expression tag |
Pro 1217 | - | expression tag |
Arg 1218 | - | expression tag |
Asp 1219 | - | expression tag |
Gly 1220 | - | expression tag |
Gln 1221 | - | expression tag |
Ala 1222 | - | expression tag |
Tyr 1223 | - | expression tag |
Val 1224 | - | expression tag |
Arg 1225 | - | expression tag |
Lys 1226 | - | expression tag |
Asp 1227 | - | expression tag |
Gly 1228 | - | expression tag |
Glu 1229 | - | expression tag |
Trp 1230 | - | expression tag |
Val 1231 | - | expression tag |
Phe 1232 | - | expression tag |
Leu 1233 | - | expression tag |
Ser 1234 | - | expression tag |
Thr 1235 | - | expression tag |
Phe 1236 | - | expression tag |
Leu 1237 | - | expression tag |
Ser 1238 | - | expression tag |
Gly 1239 | - | expression tag |
Leu 1240 | - | expression tag |
Glu 1241 | - | expression tag |
Val 1242 | - | expression tag |
Leu 1243 | - | expression tag |
Phe 1244 | - | expression tag |
Gln 1245 | - | expression tag |
Gly 1246 | - | expression tag |
Pro 1247 | - | expression tag |
Gly 1248 | - | expression tag |
Gly 1249 | - | expression tag |
Trp 1250 | - | expression tag |
Ser 1251 | - | expression tag |
His 1252 | - | expression tag |
Pro 1253 | - | expression tag |
Gln 1254 | - | expression tag |
Phe 1255 | - | expression tag |
Glu 1256 | - | expression tag |
Lys 1257 | - | expression tag |
Gly 1258 | - | expression tag |
Gly 1259 | - | expression tag |
Gly 1260 | - | expression tag |
Ser 1261 | - | expression tag |
Gly 1262 | - | expression tag |
Gly 1263 | - | expression tag |
Gly 1264 | - | expression tag |
Ser 1265 | - | expression tag |
Gly 1266 | - | expression tag |
Gly 1267 | - | expression tag |
Ser 1268 | - | expression tag |
Ala 1269 | - | expression tag |
Trp 1270 | - | expression tag |
Ser 1271 | - | expression tag |
His 1272 | - | expression tag |
Pro 1273 | - | expression tag |
Gln 1274 | - | expression tag |
Phe 1275 | - | expression tag |
Glu 1276 | - | expression tag |
Lys 1277 | - | expression tag |
Gly 1278 | - | expression tag |
Gly 1279 | - | expression tag |
Ser 1280 | - | expression tag |
His 1281 | - | expression tag |
His 1282 | - | expression tag |
His 1283 | - | expression tag |
His 1284 | - | expression tag |
His 1285 | - | expression tag |
His 1286 | - | expression tag |
His 1287 | - | expression tag |
His 1288 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 505164.5 | |
Non-Polymers* | Number of molecules | 23 |
Total formula weight | 5087.8 | |
All* | Total formula weight | 510252.3 |