7WNW
Crystal structure of Imine Reductase Mutant(M5) from Actinoalloteichus hymeniacidonis in complex with NADPH
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | 3-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase | polymer | 336 | 35260.7 | 2 | UniProt (A0A1D8BXU6) In PDB | Actinoalloteichus hymeniacidonis | Imine Reductase |
2 | B, A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
3 | water | water | 18.0 | 251 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 316 (UniProt: A0A1D8BXU6)
PDB | External Database | Details |
---|---|---|
Met -19 | - | initiating methionine |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Thr 101 | Asn 101 | engineered mutation |
Lys 125 | Gly 125 | engineered mutation |
Ala 169 | His 169 | engineered mutation |
Ile 177 | Leu 177 | engineered mutation |
Ile 187 | Phe 187 | engineered mutation |
Ala 218 | Met 218 | engineered mutation |
Phe 240 | Ser 240 | engineered mutation |
His 244 | Met 244 | engineered mutation |
His 247 | Ala 247 | engineered mutation |
Lys 251 | Asn 251 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70521.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1486.8 | |
All* | Total formula weight | 72008.1 |