7WN2

Crystal structure of SARS-CoV-2 spike receptor-binding domain (RBD) in complex with NCV2SG53 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (R, A)	Spike protein S1	polymer	224	25260.3	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)
2	B, E (H, B)	Fab Heavy chain	polymer	227	24241.4	2		Homo sapiens (Human)
3	C, F (L, C)	Fab Light chain	polymer	214	23119.7	2		Homo sapiens (Human)
4	G, H, J, K, M... (R, H, A, B, C)	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
5	I, L (R, A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
6	P, Q, R, S, T... (R, H, L, A, B...)	water	water		18.0	244	Chemie (HOH)

Sequence modifications

R, A: 321 - 536 (UniProt: P0DTC2)

PDB	External Database	Details
Thr 537	-	expression tag
Gly 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	145242.8
Non-Polymers*	Number of molecules	9
	Total formula weight	1114.9
All*	Total formula weight	146357.7

*Water molecules are not included.