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7WMO

A novel chemical derivative(92) of THRB agonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Isoform Beta-2 of Thyroid hormone receptor betapolymer26029411.01UniProt (P10828)
Pfam (PF00104)
Homo sapiens (human)
2B
(B)
Nuclear receptor coactivator 2polymer111349.61UniProt (Q15596)Homo sapiens (human)
3C
(A)
2-[[1-ethoxy-7-[4-(3-fluoranyl-5-methoxy-phenyl)carbonyl-2,6-dimethyl-phenoxy]-4-oxidanyl-isoquinolin-3-yl]carbonylamino]ethanoic acidnon-polymer562.51Chemie (9IW)
4D, E
(A, B)
waterwater18.065Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight30760.6
Non-Polymers*Number of molecules1
Total formula weight562.5
All*Total formula weight31323.1
*Water molecules are not included.

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PDB entries from 2025-12-24

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