7WMF
Threonyl-tRNA synthetase from Salmonella enterica in complex with an inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Threonine--tRNA ligase | polymer | 411 | 47964.5 | 2 | UniProt (V7II86) Pfam (PF00587) Pfam (PF03129) | Salmonella enterica subsp. enterica serovar Cubana str. 76814 | Threonyl-tRNA synthetase,ThrRS |
| 2 | C, F (A, B) | (2S,3R)-2-azanyl-N-[(1R)-2-[3-[6,7-bis(chloranyl)-4-oxidanylidene-quinazolin-3-yl]propanoylamino]-1-[3-[4-(trifluoromethyl)phenyl]phenyl]ethyl]-3-oxidanyl-butanamide | non-polymer | 650.5 | 2 | Chemie (9I9) | |||
| 3 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | E, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A, B: 242 - 642 (UniProt: V7II86)
| PDB | External Database | Details |
|---|---|---|
| Met 240 | - | initiating methionine |
| Gly 241 | - | expression tag |
| Leu 643 | - | expression tag |
| Glu 644 | - | expression tag |
| His 645 | - | expression tag |
| His 646 | - | expression tag |
| His 647 | - | expression tag |
| His 648 | - | expression tag |
| His 649 | - | expression tag |
| His 650 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 95929.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1493.8 | |
| All* | Total formula weight | 97422.9 |
