7WM4
Cryo-EM structure of tetrameric TLR3 in complex with dsRNA (90 bp)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (C, D, E, F) | Toll-like receptor 3 | polymer | 680 | 77365.9 | 4 | UniProt (Q99MB1) Pfam (PF13855) Pfam (PF00560) | Mus musculus (house mouse) | |
| 2 | E (A) | RNA (81-MER) | polymer | 81 | 25699.1 | 1 | synthetic construct | ||
| 3 | F (B) | RNA (81-MER) | polymer | 81 | 25676.1 | 1 | synthetic construct | ||
| 4 | AA, EA, FA, G, GA... (a, e, f, G, g...) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 14 | In PDB GlyTouCan (G15407YE) | |||
| 5 | BA, CA, DA, H, HA... (b, c, d, H, h...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 14 | In PDB GlyTouCan (G42666HT) | |||
| 6 | IA, JA, KA, LA, MA... (C, D, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 360838.6 | |
| Branched | Number of molecules | 28 |
| Total formula weight | 14153.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 377646.3 |
