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7WLK

CryoEM structure of human low-voltage activated T-type calcium channel Cav3.3 in complex with Otilonium Bromide(OB)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Voltage-dependent T-type calcium channel subunit alpha-1Ipolymer2223245373.01UniProt (Q9P0X4)
Pfam (PF00520)
Pfam (PF08016)
Homo sapiens (human)Voltage-gated calcium channel subunit alpha Cav3.3,Ca(v)3.3
2B
(A)
2-[diethyl(methyl)-$l^{4}-azanyl]ethyl 4-[(2-octoxyphenyl)carbonylamino]benzoatenon-polymer483.71Chemie (7TB)
3C, D, F, G, H...
(A)
1,2-Distearoyl-sn-glycerophosphoethanolaminenon-polymer748.16Chemie (3PE)
4E, R
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
5I, J, K, M, O...
(A)
CHOLESTEROL HEMISUCCINATEnon-polymer486.76Chemie (Y01)
6L, N
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight245373.0
Non-Polymers*Number of molecules17
Total formula weight8415.0
All*Total formula weight253788.0
*Water molecules are not included.

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