7WIH
Cryo-EM structure of LY2794193-bound mGlu3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Metabotropic glutamate receptor 3 | polymer | 887 | 100021.7 | 2 | UniProt (Q14832) Pfam (PF01094) Pfam (PF07562) Pfam (PF00003) | Homo sapiens (human) | mGluR3 |
| 2 | C, E (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | D, F (A, B) | (1S,2S,4S,5R,6S)-2-amino-4-[(3-methoxybenzene-1-carbonyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic acid | non-polymer | 334.3 | 2 | Chemie (CWY) |
Sequence modifications
A, B: 23 - 879 (UniProt: Q14832)
| PDB | External Database | Details |
|---|---|---|
| Met -7 | - | initiating methionine |
| Lys -6 | - | expression tag |
| Thr -5 | - | expression tag |
| Ile -4 | - | expression tag |
| Ile -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Tyr 1 | - | expression tag |
| Ile 2 | - | expression tag |
| Phe 3 | - | expression tag |
| Cys 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Val 6 | - | expression tag |
| Phe 7 | - | expression tag |
| Ala 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Tyr 10 | - | expression tag |
| Lys 11 | - | expression tag |
| Asp 12 | - | expression tag |
| Asp 13 | - | expression tag |
| Asp 14 | - | expression tag |
| Asp 15 | - | expression tag |
| Glu 16 | - | expression tag |
| Asn 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Tyr 19 | - | expression tag |
| Phe 20 | - | expression tag |
| Gln 21 | - | expression tag |
| Gly 22 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 200043.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1111.1 | |
| All* | Total formula weight | 201154.5 |
