7WHB
SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (3U)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1120 | 124037.4 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 2 | D, F, H (D, G, J) | antibody ZB8 heavy chain | polymer | 224 | 23465.4 | 3 | Homo sapiens | ||
| 3 | E, G, I (E, H, K) | antibody ZB8 light chain | polymer | 214 | 23347.0 | 3 | Homo sapiens | ||
| 4 | AA, J, K, L, M... (a, F, I, L, M...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 18 | In PDB GlyTouCan (G42666HT) | |||
| 5 | BA, CA, DA, EA, FA... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 18 | Chemie (NAG) |
Sequence modifications
A, B, C: 27 - 1146 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 512549.2 | |
| Branched | Number of molecules | 18 |
| Total formula weight | 7639.2 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3981.7 | |
| All* | Total formula weight | 524170.1 |
