7WGQ
X-ray structure of human PPAR gamma ligand binding domain-pemafibrate co-crystals obtained by co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 1 of Peroxisome proliferator-activated receptor gamma | polymer | 279 | 31863.0 | 1 | UniProt (P37231-2) Pfam (PF00104) UniProt (by SIFTS) (P37231) | Homo sapiens (human) | PPAR-gamma |
| 2 | B (B) | 15-meric peptide from Nuclear receptor coactivator 1 | polymer | 15 | 1848.2 | 1 | UniProt (Q15788) | Homo sapiens | |
| 3 | C (A) | (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid | non-polymer | 490.5 | 1 | Chemie (P7F) | |||
| 4 | D (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 203 - 477 (UniProt: P37231-2)
| PDB | External Database | Details |
|---|---|---|
| Gly 199 | - | expression tag |
| Ser 200 | - | expression tag |
| His 201 | - | expression tag |
| Met 202 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33711.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 490.5 | |
| All* | Total formula weight | 34201.7 |
