7WGN
X-ray structure of human PPAR delta ligand binding domain-pemafibrate co-crystals obtained by co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor delta | polymer | 276 | 31527.6 | 1 | UniProt (Q03181) Pfam (PF00104) | Homo sapiens (human) | PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta |
| 2 | B (A) | (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid | non-polymer | 490.5 | 1 | Chemie (P7F) | |||
| 3 | C (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 1 | Chemie (BOG) | |||
| 4 | D (A) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence modifications
A: 170 - 441 (UniProt: Q03181)
| PDB | External Database | Details |
|---|---|---|
| Gly 166 | - | expression tag |
| Ser 167 | - | expression tag |
| His 168 | - | expression tag |
| Met 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31527.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 782.9 | |
| All* | Total formula weight | 32310.6 |
