7WGL
X-ray structure of human PPAR delta ligand binding domain-bezafibrate co-crystals obtained by co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor delta | polymer | 276 | 31527.6 | 2 | UniProt (Q03181) Pfam (PF00104) | Homo sapiens (human) | PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta |
| 2 | C, E (A, B) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 2 | Chemie (BOG) | |||
| 3 | D, F (A, B) | 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID | non-polymer | 361.8 | 2 | Chemie (PEM) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
A, B: 170 - 441 (UniProt: Q03181)
| PDB | External Database | Details |
|---|---|---|
| Gly 166 | - | expression tag |
| Ser 167 | - | expression tag |
| His 168 | - | expression tag |
| Met 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63055.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1308.4 | |
| All* | Total formula weight | 64363.7 |
