7WGC

Neutral Omicron Spike Trimer in complex with ACE2.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Processed angiotensin-converting enzyme 2	polymer	594	68804.3	1	UniProt (Q9BYF1) Pfam (PF01401)	Homo sapiens (human)
2	B (C)	Spike glycoprotein	polymer	1270	141362.0	1	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2	S glycoprotein,E2,Peplomer protein
3	C, D, E, F, G (A, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)

Sequence modifications

C: 4 - 1273 (UniProt: P0DTC2)

PDB	External Database	Details
Val 70	Ala 67	variant
-	His 69	deletion
-	Val 70	deletion
Ile 96	Thr 95	variant
Asp 143	Gly 142	variant
-	Val 143	deletion
-	Tyr 144	deletion
Ile 209	-	insertion
Val 210	-	insertion
Arg 211	Asn 211	conflict
Glu 212	Leu 212	conflict
Pro 213	Val 213	conflict
Glu 214	Arg 214	conflict
Asp 339	Gly 339	variant
Leu 371	Ser 371	variant
Pro 373	Ser 373	variant
Phe 375	Ser 375	variant
Asn 417	Lys 417	variant
Lys 440	Asn 440	variant
Ser 446	Gly 446	variant
Asn 477	Ser 477	variant
Lys 478	Thr 478	variant
Ala 484	Glu 484	variant
Arg 493	Gln 493	variant
Ser 496	Gly 496	variant
Arg 498	Gln 498	variant
Tyr 501	Asn 501	variant
His 505	Tyr 505	variant
Lys 547	Thr 547	variant
Gly 614	Asp 614	variant
Tyr 655	His 655	variant
Lys 679	Asn 679	variant
His 681	Pro 681	variant
Ala 683	Arg 683	variant
Ala 685	Arg 685	variant
Lys 764	Asn 764	variant
Tyr 796	Asp 796	variant
Lys 856	Asn 856	variant
Pro 892	Ala 892	variant
Pro 899	Ala 899	variant
Pro 942	Ala 942	variant
His 954	Gln 954	variant
Lys 969	Asn 969	variant
Phe 981	Leu 981	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	210166.3
Non-Polymers*	Number of molecules	5
	Total formula weight	1106.0
All*	Total formula weight	211272.4

*Water molecules are not included.