7WFY
Crystal Structure of the VAV2 SH2 domain in complex with APP phosphorylated peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Guanine nucleotide exchange factor VAV2 | polymer | 117 | 13893.7 | 1 | UniProt (P52735) Pfam (PF00017) | Homo sapiens (human) | VAV-2 |
| 2 | B (A) | Amyloid beta A4 protein-binding family B member 1 (protein) | polymer | 8 | 1001.9 | 1 | UniProt (by SIFTS) (P05067) | Homo sapiens | |
| 3 | C, D (C, A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
C: 659 - 771 (UniProt: P52735)
| PDB | External Database | Details |
|---|---|---|
| Gly 655 | - | expression tag |
| Ser 656 | - | expression tag |
| His 657 | - | expression tag |
| Met 658 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14895.6 | |
| All* | Total formula weight | 14895.6 |
