7WE4
Human Nav1.8 with A-803467, class I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium channel protein type 10 subunit alpha | polymer | 1956 | 220903.5 | 1 | UniProt (Q9Y5Y9) Pfam (PF00520) Pfam (PF06512) Pfam (PF08016) | Homo sapiens (human) | Peripheral nerve sodium channel 3,PN3,hPN3,Sodium channel protein type X subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.8 |
| 2 | B, C (B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D, E, F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 4 | G (A) | 5-(4-chlorophenyl)-~{N}-(3,5-dimethoxyphenyl)furan-2-carboxamide | non-polymer | 357.8 | 1 | Chemie (95T) | |||
| 5 | BA, H, S, X (A) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) | |||
| 6 | I, J, M, P, Q (A) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 5 | Chemie (PCW) | |||
| 7 | K, L, N, O, R... (A) | 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 510.7 | 9 | Chemie (LPE) | |||
| 8 | AA, Y, Z (A) | O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine | non-polymer | 792.1 | 3 | Chemie (P5S) |
Sequence modifications
A: 1 - 1956 (UniProt: Q9Y5Y9)
| PDB | External Database | Details |
|---|---|---|
| Phe 894 | Ser 894 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 220903.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 13476.2 | |
| All* | Total formula weight | 235228.5 |
