7WCQ
Crystal structure of HIV-1 protease in complex with lactam derivative 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protease | polymer | 99 | 10830.8 | 1 | UniProt (Q9WFL7) Pfam (PF00077) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus | Retropepsin |
| 2 | B (A) | (3R,4R)-3-[(4-fluorophenyl)methyl]-1-[(4-methoxyphenyl)methyl]-3-(4-methylsulfonylphenyl)-4-oxidanyl-pyrrolidin-2-one | non-polymer | 483.6 | 1 | Chemie (8OC) | |||
| 3 | C (A) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10830.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 483.6 | |
| All* | Total formula weight | 11314.3 |
