7WBQ
Crystal structure of the receptor binding domain of SARS-CoV-2 Delta variant spike glycoprotein in complex with its receptor human ACE2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Angiotensin-converting enzyme 2 | polymer | 596 | 69038.6 | 2 | UniProt (Q9BYF1) Pfam (PF01401) In PDB | Homo sapiens (human) | ACE-related carboxypeptidase,Angiotensin-converting enzyme homolog |
| 2 | B, D | Spike protein S1 | polymer | 223 | 25194.4 | 2 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 | |
| 3 | E, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F | beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G61843VN) | |||
| 5 | A, C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 6 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
B, D: 319 - 541 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Arg 452 | Leu 452 | variant |
| Lys 478 | Thr 478 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 188466.0 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1216.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2342.9 | |
| All* | Total formula weight | 192025.1 |
