7WA1

Structure of SARS-CoV-2 spike receptor-binding domain F486L mutation complexed with American mink ACE2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Angiotensin-converting enzyme 2	polymer	603	70562.2	1	Pfam (PF01401) UniProt (by SIFTS) (A0A8C7BTF2) In PDB	Homo sapiens
2	B	Spike protein S1	polymer	229	25917.2	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2
3	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)

Sequence modifications

B: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Leu 486	Phe 486	engineered mutation
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	96479.4
Non-Polymers*	Number of molecules	1
	Total formula weight	65.4
All*	Total formula weight	96544.8

*Water molecules are not included.