7W9S

Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Genome polyprotein	polymer	468	53408.5	1	UniProt (E5RPG3) Pfam (PF00680) In PDB	Enterovirus A71
2	B	RNA (35-MER)	polymer	35	11260.7	1		synthetic construct
3	C	RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*CP*U)-3')	polymer	17	5506.4	1		synthetic construct
4	A	CYTIDINE-5'-TRIPHOSPHATE	non-polymer		483.2	1	Chemie (CTP)
5	A	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
6	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
7	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
8		water	water		18.0	16	Chemie (HOH)

Sequence modifications

A: 1 - 462 (UniProt: E5RPG3)

PDB	External Database	Details
Met 291	Cys 2022	engineered mutation
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	70175.5
Non-Polymers*	Number of molecules	7
	Total formula weight	885.4
All*	Total formula weight	71060.9

*Water molecules are not included.