7W7Y
The crystal structure of human abl1 kinase domain in complex with ABL2-A5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tyrosine-protein kinase ABL1 | polymer | 276 | 32061.5 | 2 | UniProt (P00519) Pfam (PF07714) | Homo sapiens (human) | Abelson murine leukemia viral oncogene homolog 1,Abelson tyrosine-protein kinase 1,Proto-oncogene c-Abl,p150 |
| 2 | C, D (A, B) | 5-[3-(5-methanoyl-2-methoxy-4-oxidanyl-phenyl)-1~{H}-pyrrolo[2,3-b]pyridin-5-yl]-~{N},~{N}-dimethyl-pyridine-3-carboxamide | non-polymer | 416.4 | 2 | Chemie (8IW) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 384 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64123.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 832.9 | |
| All* | Total formula weight | 64955.9 |
