7W6S

CryoEM structure of human KChIP2-Kv4.3 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, C, E, G)	Kv channel-interacting protein 2	polymer	286	32693.6	4	UniProt (Q9NS61) Pfam (PF13833) Pfam (PF13499)	Homo sapiens (human)	KChIP2,A-type potassium channel modulatory protein 2,Cardiac voltage-gated potassium channel modulatory subunit,Potassium channel-interacting protein 2
2	B, D, F, H (B, D, F, H)	Isoform 2 of Potassium voltage-gated channel subfamily D member 3	polymer	636	71472.8	4	UniProt (Q9UK17) Pfam (PF11601) Pfam (PF02214) Pfam (PF00520) Pfam (PF07885) Pfam (PF11879)	Homo sapiens (human)	Voltage-gated potassium channel subunit Kv4.3

Sequence modifications

A, C, E, G: 1 - 270 (UniProt: Q9NS61)

PDB	External Database	Details
Leu 271	-	expression tag
Glu 272	-	expression tag
Gly 273	-	expression tag
Gly 274	-	expression tag
Ser 275	-	expression tag
Ser 276	-	expression tag
Gly 277	-	expression tag
Gly 278	-	expression tag
His 279	-	expression tag
His 280	-	expression tag
His 281	-	expression tag
His 282	-	expression tag
His 283	-	expression tag
His 284	-	expression tag
His 285	-	expression tag
His 286	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	416665.5
All*	Total formula weight	416665.5

*Water molecules are not included.