7W6G
TKS-L190G mutant from Cannabis sativa in complex with lauroyl-CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3,5,7-trioxododecanoyl-CoA synthase | polymer | 385 | 42618.0 | 4 | UniProt (B1Q2B6) Pfam (PF00195) Pfam (PF02797) | Cannabis sativa | Olivetol synthase,Polyketide synthase-1,Tetraketide synthase |
| 2 | E, F, H, J, N (A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 3 | G, K, L, M, Q... (A, C, D) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 4 | I, R (C, D) | ~{S}-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] tridecanethioate | non-polymer | 963.9 | 2 | Chemie (8I9) | |||
| 5 | O (C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | P (C) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 7 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 621 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 385 (UniProt: B1Q2B6)
| PDB | External Database | Details |
|---|---|---|
| Gly 190 | Leu 190 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170471.9 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3627.6 | |
| All* | Total formula weight | 174099.5 |
