7W2G
An open-like conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 by soaking
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Sigma non-opioid intracellular receptor 1 | polymer | 225 | 25121.7 | 12 | UniProt (Q6DCU6) Pfam (PF04622) | Xenopus laevis (African clawed frog) | Sigma 1-type opioid receptor,Sigma1-receptor,Sigma1R |
| 2 | AA, CA, EA, M, N... (J, K, L, A, B...) | 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate | non-polymer | 317.4 | 12 | Chemie (E84) | |||
| 3 | BA, DA, O, S, V... (J, K, B, E, G...) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 7 | Chemie (BOG) | |||
| 4 | FA, GA, HA, IA, JA... (A, B, C, D, E...) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 221 (UniProt: Q6DCU6)
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | - | expression tag |
| Val -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 301460.2 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 5855.7 | |
| All* | Total formula weight | 307315.8 |
