7W2D
The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with S1RA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, B, D... | Sigma non-opioid intracellular receptor 1 | polymer | 225 | 25121.7 | 12 | UniProt (Q6DCU6) Pfam (PF04622) In PDB | Xenopus laevis (African clawed frog) | Sigma 1-type opioid receptor,Sigma1-receptor,Sigma1R |
| 2 | F, G, H, I, A... | GOLD ION | non-polymer | 197.0 | 24 | Chemie (AU) | |||
| 3 | D, F, G, H, I... | 4-[2-(5-methyl-1-naphthalen-2-yl-pyrazol-3-yl)oxyethyl]morpholine | non-polymer | 337.4 | 12 | Chemie (88E) |
Sequence modifications
A, C, E, B, D, F, G, H, I, J, K, L: 1 - 221 (UniProt: Q6DCU6)
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | - | expression tag |
| Val -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 301460.2 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 8776.2 | |
| All* | Total formula weight | 310236.4 |
