7W1W

NADPH-bound AKR4C17 mutant F291D

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	AKR4-2	polymer	321	35312.0	2	UniProt (A0A5J6VLZ7) Pfam (PF00248) In PDB	Echinochloa colona
2	A, B	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	2	Chemie (NDP)
3		water	water		18.0	881	Chemie (HOH)

Sequence modifications

A, B: 1 - 310 (UniProt: A0A5J6VLZ7)

PDB	External Database	Details
Gly -10	-	expression tag
Ala -9	-	expression tag
Gly -8	-	expression tag
Ala -7	-	expression tag
Gly -6	-	expression tag
Ala -5	-	expression tag
Gly -4	-	expression tag
Ala -3	-	expression tag
Gly -2	-	expression tag
Ala -1	-	expression tag
Gly 0	-	expression tag
Asp 291	Phe 291	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70624.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1490.8
All*	Total formula weight	72114.9

*Water molecules are not included.