7W1A
Crystal Structure of MPH-E in complex with GMP and Azithromycin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | Macrolide 2'-phosphotransferase | polymer | 302 | 34619.6 | 2 | UniProt (A5Y459) Pfam (PF01636) In PDB | Acinetobacter baumannii | Macrolide 2'-phosphotransferase,Mph(E)/Mph(G) family,Mph(E) family macrolide 2'-phosphotransferase,Mph(E) macrolide 2'-phosphotransferase,Mph2,Putative aminoglycoside phosphotransferase |
2 | B, A | GUANOSINE | non-polymer | 283.2 | 2 | Chemie (GMP) | |||
3 | B, A | AZITHROMYCIN | non-polymer | 749.0 | 2 | Chemie (ZIT) | |||
4 | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 294 (UniProt: A5Y459)
PDB | External Database | Details |
---|---|---|
Leu 295 | - | expression tag |
Glu 296 | - | expression tag |
His 297 | - | expression tag |
His 298 | - | expression tag |
His 299 | - | expression tag |
His 300 | - | expression tag |
His 301 | - | expression tag |
His 302 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 69239.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 2064.4 | |
All* | Total formula weight | 71303.6 |