7W15

Crystal Structure of MPH-E in complex with GTP and Erythromycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	Macrolide 2'-phosphotransferase	polymer	302	34619.6	2	UniProt (A5Y459) Pfam (PF01636)	Acinetobacter baumannii	Macrolide 2'-phosphotransferase,Mph(E)/Mph(G) family,Mph(E) family macrolide 2'-phosphotransferase,Mph(E) macrolide 2'-phosphotransferase,Mph2,Putative aminoglycoside phosphotransferase
2	C, J (B, A)	ERYTHROMYCIN A	non-polymer		733.9	2	Chemie (ERY)
3	D, K (B, A)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
4	E, F, G, L, M... (B, A)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
5	H, I (B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	O, P (B, A)	water	water		18.0	833	Chemie (HOH)

Sequence modifications

B, A: 1 - 294 (UniProt: A5Y459)

PDB	External Database	Details
Leu 295	-	expression tag
Glu 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag
His 302	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69239.2
Non-Polymers*	Number of molecules	12
	Total formula weight	2844.2
All*	Total formula weight	72083.4

*Water molecules are not included.