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7VWF

Human peroxisome proliferator-activated receptor (PPAR) delta ligand binding domain in complex with a synthetic agonist TIPP204

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor deltapolymer27631527.62UniProt (Q03181)
Pfam (PF00104)
Homo sapiens (Human)PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta
2C, E
(A, B)
heptyl beta-D-glucopyranosidenon-polymer278.32Chemie (B7G)
3D, F
(A, B)
(2S)-2-{4-butoxy-3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]benzyl}butanoic acidnon-polymer469.52Chemie (K55)
4G, H
(A, B)
waterwater18.0215Chemie (HOH)
Sequence modifications
A, B: 206 - 477 (UniProt: Q03181)
PDBExternal DatabaseDetails
Gly 202-expression tag
Ser 203-expression tag
His 204-expression tag
Met 205-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63055.3
Non-Polymers*Number of molecules4
Total formula weight1495.6
All*Total formula weight64550.9
*Water molecules are not included.

250835

PDB entries from 2026-03-18

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