7VUO
Crystal Structure of the Kv7.1 C-terminal Domain in Complex with Calmodulin disease mutation F141L
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kv7.1 | polymer | 69 | 8122.4 | 1 | UniProt (by SIFTS) (P51787) | Homo sapiens (Human) | |
| 2 | B (C) | Calmodulin-1 | polymer | 148 | 16687.3 | 1 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (Human) | |
| 3 | C, D (C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E, F (A, C) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
C: 1 - 148 (UniProt: P0DP23)
| PDB | External Database | Details |
|---|---|---|
| Leu 141 | Phe 142 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 24809.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 24889.9 |
