7VTV
Crystal structure of PDE8A catalytic domain in complex with 15
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | polymer | 338 | 39090.0 | 1 | UniProt (O60658) Pfam (PF00233) In PDB | Homo sapiens (Human) | |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | A | 2-chloro-9-(3-(2,2-difluoroethoxy)-5-(difluoromethoxy)benzyl)-9H-purin-6-amine | non-polymer | 405.7 | 1 | Chemie (7ZZ) | |||
5 | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39090.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 495.4 | |
All* | Total formula weight | 39585.5 |