7VSL
Crystal structure of PDE8A catalytic domain in complex with 10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | polymer | 338 | 39090.0 | 1 | UniProt (O60658) Pfam (PF00233) | Homo sapiens (Human) | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | 2-chloro-9-(3-(2,2-difluoroethoxy)benzyl)-9H-purin-6-amine | non-polymer | 339.7 | 1 | Chemie (7XI) | |||
| 5 | E (A) | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39090.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 429.4 | |
| All* | Total formula weight | 39519.5 |
