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7VSI

Structure of human SGLT2-MAP17 complex bound with empagliflozin

Replaces:  7FEN
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sodium/glucose cotransporter 2polymer67272949.41UniProt (P31639)
Pfam (PF00474)
Homo sapiens (Human)Na(+)/glucose cotransporter 2,Low affinity sodium-glucose cotransporter,Solute carrier family 5 member 2
2B
(B)
PDZK1-interacting protein 1polymer565937.11UniProt (Q13113)
Pfam (PF15807)
Homo sapiens (Human)17 kDa membrane-associated protein,Protein DD96
3C, D
(A)
PALMITIC ACIDnon-polymer256.42Chemie (PLM)
4E
(A)
(2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triolnon-polymer450.91Chemie (7R3)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight78886.5
Non-Polymers*Number of molecules3
Total formula weight963.8
All*Total formula weight79850.3
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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