7VRS

The complex of Acyltransferase and Acyl Carrier Protein Domains from module 9 of Salinomycin Polyketide Synthase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Type I modular polyketide synthase	polymer	466	48557.4	2	UniProt (H1ZZT7) Pfam (PF16197) Pfam (PF00698) UniProt (by SIFTS) (H6D573) In PDB	Streptomyces albus subsp. albus
2	C	Type I modular polyketide synthase	polymer	107	11283.7	1	UniProt (H1ZZT7) Pfam (PF00550) UniProt (by SIFTS) (H6D573) In PDB	Streptomyces albus subsp. albus
3	A, B	1,1'-butane-1,4-diylbis(1H-pyrrole-2,5-dione)	non-polymer		248.2	2	Chemie (ME9)
4	C	4'-PHOSPHOPANTETHEINE	non-polymer		358.3	1	Chemie (PNS)
5		water	water		18.0	119	Chemie (HOH)

Sequence modifications

A, B: 0 - 444 (UniProt: H1ZZT7)

PDB	External Database	Details
Met -21	-	initiating methionine
Gly -20	-	expression tag
Ser -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Leu -8	-	expression tag
Val -7	-	expression tag
Pro -6	-	expression tag
Arg -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
His -2	-	expression tag
Met -1	-	expression tag
Cys 190	Ser 2773	engineered mutation
Ser 298	Cys 2881	engineered mutation
Ser 347	Cys 2930	engineered mutation

C: 3 - 88 (UniProt: H1ZZT7)

PDB	External Database	Details
Met -18	-	initiating methionine
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
His 1	-	expression tag
Met 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	108398.5
Non-Polymers*	Number of molecules	3
	Total formula weight	854.8
All*	Total formula weight	109253.3

*Water molecules are not included.