7VRO
crystal structure of BRD2-BD1 in complex with purine derivative
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Bromodomain-containing protein 2 | polymer | 126 | 14885.3 | 3 | UniProt (P25440) Pfam (PF00439) | Homo sapiens (Human) | |
| 2 | D, E, H, K (A, B, C) | THEOBROMINE | non-polymer | 180.2 | 4 | Chemie (37T) | |||
| 3 | F, G, I, J (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | L, M, N (A, B, C) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A, B, C: 73 - 194 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Gly 69 | - | expression tag |
| Ser 70 | - | expression tag |
| His 71 | - | expression tag |
| Met 72 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44656.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1104.9 | |
| All* | Total formula weight | 45760.9 |
