7VMB

Crystal structure of IQSEC1-IQ motif, Sec7PH tandem in complex with calmodulin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	IQ motif and SEC7 domain-containing protein 1	polymer	372	43256.0	1	UniProt (Q6DN90) Pfam (PF01369) Pfam (PF16453) In PDB	Homo sapiens (Human)	ADP-ribosylation factors guanine nucleotide-exchange protein 100,ADP-ribosylation factors guanine nucleotide-exchange protein 2,Brefeldin-resistant Arf-GEF 2 protein,BRAG2
2	B	IQ motif and SEC7 domain-containing protein 1	polymer	74	8716.8	1	UniProt (Q6DN90) In PDB	Homo sapiens (Human)	ADP-ribosylation factors guanine nucleotide-exchange protein 100,ADP-ribosylation factors guanine nucleotide-exchange protein 2,Brefeldin-resistant Arf-GEF 2 protein,BRAG2
3	C	Calmodulin-1	polymer	153	17150.8	1	UniProt (P0DP23) Pfam (PF13499) In PDB	Homo sapiens (Human)
4	A	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5		water	water		18.0	268	Chemie (HOH)

Sequence modifications

A: 517 - 882 (UniProt: Q6DN90)

PDB	External Database	Details
Gly 511	-	expression tag
Pro 512	-	expression tag
Gly 513	-	expression tag
Ser 514	-	expression tag
Glu 515	-	expression tag
Phe 516	-	expression tag

B: 106 - 173 (UniProt: Q6DN90)

PDB	External Database	Details
Gly 100	-	expression tag
Pro 101	-	expression tag
Gly 102	-	expression tag
Ser 103	-	expression tag
Glu 104	-	expression tag
Phe 105	-	expression tag

C: 0 - 148 (UniProt: P0DP23)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	69123.7
Non-Polymers*	Number of molecules	3
	Total formula weight	276.3
All*	Total formula weight	69400.0

*Water molecules are not included.