7VM6
Crystal structure of uPA in complex with 6-amidino-2-naphthol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (U) | Urokinase-type plasminogen activator chain B | polymer | 248 | 27973.8 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (Human) | |
2 | B (U) | 6-oxidanylnaphthalene-2-carboximidamide | non-polymer | 186.2 | 1 | Chemie (7R8) | |||
3 | C (U) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
4 | D (U) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
5 | E (U) | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
U: 16 - 245 (UniProt: P00749)
PDB | External Database | Details |
---|---|---|
Ala 122 | Cys 299 | conflict |
Gln 145 | Asn 322 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 27973.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 432.4 | |
All* | Total formula weight | 28406.3 |