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7VM6

Crystal structure of uPA in complex with 6-amidino-2-naphthol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(U)
Urokinase-type plasminogen activator chain Bpolymer24827973.81UniProt (P00749)
Pfam (PF00089)
Homo sapiens (Human)
2B
(U)
6-oxidanylnaphthalene-2-carboximidamidenon-polymer186.21Chemie (7R8)
3C
(U)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(U)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
5E
(U)
waterwater18.0140Chemie (HOH)
Sequence modifications
U: 16 - 245 (UniProt: P00749)
PDBExternal DatabaseDetails
Ala 122Cys 299conflict
Gln 145Asn 322conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight27973.8
Non-Polymers*Number of molecules3
Total formula weight432.4
All*Total formula weight28406.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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