7VLK

eIF2B-SFSV NSs C2-imposed

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Translation initiation factor eIF-2B subunit alpha	polymer	307	33908.3	2	UniProt (Q14232) Pfam (PF01008) In PDB	Homo sapiens (Human)	eIF-2B GDP-GTP exchange factor subunit alpha
2	C, D	Translation initiation factor eIF-2B subunit beta	polymer	351	39039.5	2	UniProt (P49770) Pfam (PF01008) In PDB	Homo sapiens (Human)	S20I15,S20III15,eIF-2B GDP-GTP exchange factor subunit beta
3	E, F	Translation initiation factor eIF-2B subunit gamma	polymer	452	50304.2	2	UniProt (Q9NR50) Pfam (PF00483) In PDB	Homo sapiens (Human)	eIF2Bg,eIF-2B GDP-GTP exchange factor subunit gamma
4	G, H	Translation initiation factor eIF-2B subunit delta	polymer	523	57640.2	2	UniProt (Q9UI10) Pfam (PF01008) In PDB	Homo sapiens (Human)	eIF-2B GDP-GTP exchange factor subunit delta
5	I, J	Translation initiation factor eIF-2B subunit epsilon	polymer	721	80466.6	2	UniProt (Q13144) Pfam (PF02020) In PDB	Homo sapiens (Human)	eIF-2B GDP-GTP exchange factor subunit epsilon
6	K, L	Non-structural protein NS-S	polymer	261	29695.4	2	UniProt (P12792) Pfam (PF11073) In PDB	Sandfly fever sicilian virus (SFS)

Sequence modifications

A, B: 1 - 305 (UniProt: Q14232)

PDB	External Database	Details
Gly -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	582108.5
All*	Total formula weight	582108.5

*Water molecules are not included.