7VK9
Crystal structure of xCas9 P411T
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | CRISPR-associated endonuclease Cas9/Csn1 | polymer | 1368 | 158653.9 | 1 | UniProt (Q99ZW2) Pfam (PF16593) Pfam (PF16592) Pfam (PF13395) Pfam (PF22702) Pfam (PF16595) In PDB | Streptococcus pyogenes serotype M1 | SpCas9,SpyCas9 |
| 2 | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 21 - 1388 (UniProt: Q99ZW2)
| PDB | External Database | Details |
|---|---|---|
| Thr 282 | Ala 262 | engineered mutation |
| Leu 344 | Arg 324 | engineered mutation |
| Ile 429 | Ser 409 | engineered mutation |
| Thr 431 | Pro 411 | engineered mutation |
| Lys 500 | Glu 480 | engineered mutation |
| Asp 563 | Glu 543 | engineered mutation |
| Ile 714 | Met 694 | engineered mutation |
| Val 1239 | Glu 1219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 158653.9 | |
| All* | Total formula weight | 158653.9 |
